PUBLICATIONS

Featured Recent Publications

Maynard, J.A., Leppla, S.H., Brasky, K., Patterson, J.L., Iverson, B.L. and Georgiou, G. (2002) Recombinant Antibody Fragment Mediated Protection to Anthrax Toxin Challenge Correlates with Antigen Affinity. Nature/Biotechnology. 20, 597–601. DOI: 10.1038/nbt0602-597.

Mabry, R., Rani, M., Geiger, R., Hubbard, G.B., Carrion R., Jr., Brasky, K., Patterson, J.L., Georgiou, G., Iverson, B.L. (2005) Passive Protection Against Anthrax Using a High Affinity Anti-Toxin Antibody, Fragment Lacking An Fc Region. Infection and Immunity. 73, 8362-8368. DOI: 10.1128/IAI.73.12.8362-8368.2005.

Mazor Y, Van Blarcom T., Mabry R., Iverson B.L., Georgiou G. (2007) Isolation of Engineered, Full-length Antibodies from Libraries Expressed in Escherichia coli Nat Biotechnol. 25(5), 563-565.

Bradford, V.J. and Iverson, B.L., (2008) Amyloid-like Behavior in Abiotic, Amphiphilic Foldamers J. Am. Chem. Soc. 130(1), 1517-1524.

Varadarajan, N., Rodriguez, S., Hwang, B.W., Georgiou, G., Iverson B.L., (2008) Highly Active and Selective Endopeptidases with Programmed Substrate Specificities, Nature Chem. Biology 4, 290-294.

Yariv Mazor, Y., Van Blarcom, T., Iverson, B.L., Georgiou, G., (2008) E-clonal antibodies: selection of full-length IgG antibodies using bacterial periplasmic display, Nature Protocols, 3, 1766-1777.

Varadarajan, N., Georgiou, G., Iverson B.L., (2008) An Engineered Protease that Cleaves Specifically After Sulfated Tyrosine”, Angewandte Chemie-Int. Ed., 47, 7861-7863.

Chu, Y., Hoffman, D.W., and Iverson, B.L. (2009) A Pseudocatenane Structure Formed between DNA and a Cyclic Bisintercalator”, J. Am. Chem. Soc., 131, 3499-3508.

Pogson, M., Georgiou, G., Iverson B.L., (2009) Engineering next generation proteases, Current Op. in Biotech., 20, 390-397.

Varadarajan, N., Pogson, M., Georgiou, G., and Iverson, B.L. (2009) Proteases That Can Distinguish among Different Post-translational Forms of Tyrosine Engineered Using Multicolor Flow Cytometry J. Am. Chem. Soc., 131, 18186-18190.

Leysath, C.E., Monzingo, A.F., Maynard, J.A., Barnett, J., Georgiou, G., Iverson, B.L., and Robertus, J., (2009) Crystal Structure of the Engineered Neutralizing Antibody M18 Complexed to Domain 4 of the Anthrax Protective Antigen. J. Mol. Bio., 387, 680-693. DOI: 10.1016/j.jmb.2009.02.003.

Rhoden Smith, A.; Ikkanda, B.A.: Holman, G. and Iverson, B.L. (2012) Subtle Recognition of 14-Base Pair DNA Sequences via Threading Polyintercalation. Biochemistry, 51, 4445−4452. DOI: 10.1021/bi303317n.

Martinez, C. and Iverson, B.L. (2012) Rethinking the Term ‘Pi-stacking’, Chem. Sci., 3, 2191-2201.

Rhoden Smith, A. and Iverson, B.L. (2013) Threading Polyintercalators with Extremely Slow Dissociation Rates and Extended DNA Binding Sites. J. Am. Chem. Soc., 135, 12783-12789. DOI: 10.1021/ja4057344.

Peebles, C., Piland, R., and Iverson, B.L. (2013) More than Meets the Eye: Conformational Switching of a Stacked Dialkoxynaphthalene Naphthalenetetracarboxylic diimide (DAN–NDI) Foldamer to an NDI–NDI Fibril Aggregate. Chemistry, a European Journal. 19, 11598–11602/ PMID:23853102; DOI: 10.1002/chem.201302009.

Yi, L., Gebhard, M.C., Li. Q., Taft, J., Georgiou, G. and Iverson, B.L. (2013) Engineering of TEV protease Variants by Yeast ER Sequestration Screening (YESS) of Combinatorial Libraries. Proc. of Nat. Acad. Sci. USA, 110, 7229-7234. PMID 23589865 DOI:10.1073/pnas.1215994110.

Ikkanda, B. and Iverson B.L. (2014) NDI and DAN DNA: Nucleic Acid Directed Assembly of NDI and DAN. Org. Chem., 79, 2029–2037. DOI: 10.1021/jo402704z.

Peebles, C., Alvey, P.M., Lynch, V. and Iverson, B.L. (2014) Time-Dependent Solid-State Polymorphism of a Series of Donor–Acceptor Dyads. Cryst. Growth and Design, 14 290–299. PMID: 24678269; DOI: 10.1021/cg401522v.

Yi,L., Taft, JM., Li, Q., Gebhard, MC., Georgiou, G., Iverson, B.L. (2015) Yeast Endoplasmic Reticulum Sequestration Screening for the Engineering of Proteases from Libraries Expressed in Yeast. Methods Mol Biol. 1319:81-93. DOI: 10.1007/978-1-4939-5748.

Ikkanda, B.A and Iverson, B.L. (2016) Exploiting the Interactions of Aromatic Units for Folding and Assembly in Aqueous Environments. Chem Comm., 52, 7752-7759. PMID: 27080050; DOI: 10.1039/c6cc01861k

Li, Q., Yi, L., Hoi, KH., Marek, P., Georgiou, G., Iverson, B.L. (2017) Profiling Protease Specificity: Combining Yeast ER Sequestration Screening (YESS) with Next Generation Sequencing. ACS Chem Biol. 12(2):510-518. DOI:10:1021/acschembio.6b00547.

Taft JM, Georgeon S, Allen C, Reckel S, DeSautelle J, Hatchell O, Georgiou G, Iverson BL. (2019) Rapid Screen for Tyrosine Kinase Inhibitor Resistance Mutations and Substrate Specificity. ACS Chem Biol., 14(9):1888-1895, doi: 10.1021/acschembio.9b00283. PMID: 31339688.

Wight, CD., Xiao, Q., Wagner, HR., Hernandez, EA., Lynch, VM., Iverson, B.L. (2020) Mechanistic Analysis of Solid-State Colorimetric Switching: Monoalkoxynaphthalene-Naphthalimide Donor-Acceptor Dyads. J. Am. Chem. Soc., 142(41), 17630-17643. PMID: 32897707; DOI: 10.1021/jacs.0c08137.

C. A. Denard, C. Paresi, R. Yaghi, N. McGinnis, Z. Bennett, L. Yi, G. Georgiou, and B. L. Iverson (2021) YESS 2.0, a Tunable Platform for Enzyme Evolution, Yields Highly Active TEV Protease Variants, ACS Syn. Biol. 10, 1, 63-71. DOI: 10.1021/acssynbio.0c00452

Wi. Voss, Y. Hou, N. Johnson, G. Delidakis, JE Kim, K. Javanmardi, A. Horton, F. Bartzoka, C. Paresi, Y. Tanno, C-W. Chou, S. Abbasi, W. Pickens, K. George, D. Boutz, D. Towers, J. McDaniel, D. Billick, J. Goike, L. Rowe9, D. Batra, J. Pohl, J. Lee, S. Gangappa, S. Sambhara, M. Gadush, N. Wang, M. Person, B. L. Iverson, J. Gollihar, J. Dye, A. Herbert, I. Finkelstein, R. Baric, J. McLellan, G. Georgiou, J. Lavinder, G. Ippolito, (2021) Prevalent, Protective, and Convergent IgG Recognition of SARS-CoV-2 non-RBD Spike Epitopes Science, 372, Issue 6546, 1108-1112 DOI: 10.1126/science.abg5268